By submitting this form, you are agreeing to the Terms of Use and Privacy Policy.
.
A static light scattering detector known as a multi angle light scattering (MALS) detector may measure a sample’s absolute molecular weight (Mw) and perhaps its radius of gyration (Rg).Connecting a MALS to an HPLC size exclusion chromatography (SEC) or gel permeation chromatography (GPC) system, like OMNISEC, is the most typical way to use a MALS.
A concentration detector, either UV or Refractive index, must be linked to this system in order for it to function. In order to construct a Debye plot, the SEC-MALS detector measures the light dispersed by a sample at various angles. The Mw and Rg are calculated for each data slice in the chromatogram using the Debye plot, which simulates the angular dependence of a sample’s scattering.
The fit order and model selected for this analysis need to be thoroughly thought out because they will have a big impact on the outcomes. Smaller than 10-15 nm in radius, isotropic scatterers will evenly scatter light in all directions, allowing only the Mw to be measured.
Anisotropic scattering samples with a radius greater than 10-15 nm will scatter more light in the forward direction, enabling the measurement of both Mw and Rg. The Rg can be used to create a conformation plot (a plot of Rg against Mw), which makes it possible to measure any structural variations across samples.
Global multi angle light scattering detector market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Multi-Angle Light Scattering detectors from the PN3600 Series have been created specifically for integration with Postnova Field-Flow Fractionation separation systems. A flexible solution for all types of FFF applications is provided by the MALS Light Scattering platform, which comprises of various variations.
Based on more than two decades of actual use and hyphenation of FFF and MALS, Postnova provides the most adaptable and potent MALS solution currently available.
The top model in this PN3600 detector series, the singular PN3621 MALS, meets the strictest standards for sensitivity, precision, and adaptability and delivers singular technical features: Multi-Angle Light Scattering detectors from the PN3600 Series have been created specifically for integration with Postnova Field-Flow Fractionation separation systems.
Different versions of the MALS Light Scattering platform provide a versatile , sensitivity, flexibility and precision.
