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Chitin is a widely prevalent biopolymer that is present in the cell walls of fungus, algae, insect cuticles, and the exoskeletons of crustaceans. Less frequently seen in nature, chitosan is found in several fungi (Mucoraceae). Historically, the majority of commercially available chitosan samples were made by chemically deacetylating chitin derived from crustacean sources. Demand from vegans has recently increased market interest in chitosan derived from fungi.
Additionally, these samples have lower viscosities that are well regulated and have a very high deacetylation level. The rising interest in producing protein from these sources has led to a rise in interest in production from insect cuticles. The only polycation found in nature, chitosan’s charge density is influenced by the media’s pH and level of acetylation.
Chitosan oligomers are soluble at a variety of pH levels, including basic and acidic ones. Contrarily, even at high deacetylation levels, chitosan samples with greater Mw are only soluble in acidic aqueous conditions. Chitosan’s usage in several applications under neutral physiological circumstances has been hampered by its insolubility at neutral and basic pH.
This is the rationale behind the extensive development of chitosan derivatives with improved solubility. By deacetylating chitin, chitosan is created; during this process, certain N-acetylglucosamine moieties are changed into glucosamine units. Since chitosan’s pKa value is close to 6.5, its solubility in acidic aqueous conditions can be attributed to the structure’s abundance of protonated -NH2 groups.
The US Chitosan market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Our medical-grade chitosan is produced from pure shrimp peels and shells with unparalleled quality and traceability thanks to ground-breaking Tidal Basin indoor aquaculture technology. The ideal option for your chitosan research or application is tr Chitosan since our highly regulated environment produces superior shrimp that create superior chitosan that is naturally low in heavy metals and other contaminants.
Each product lot is examined using chitosan-specific testing procedures validated by the United States Pharmacopeia (USP) in a facility that is both FDA registered and ISO recognized. The plant and its operations are audited for compliance many times a year. Chitosan is frequently combined with other polysaccharides such as hydroxypropyl methylcellulose (HPMC), gelatin, collagen, peptides, and hyaluronic acid because it is stable under a variety of environmental conditions.
