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Nanofibers are fibres with a diameter between one nanometer and one micrometre, generally. Nanofibers can be produced from a variety of polymers, giving them a range of physical characteristics and possible uses.
A large exposed surface area and nanoporosity can be provided by nanofibrous meshes made of numerous intersecting nanofibers as small as a few microns to a few hundred nanometers, facilitating interaction with the cells present in the injured tissue or the wound bed through an ECM-mimicking structure.
The Global Antibacterial biohybrid nanofiber Market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
Antibacterial Biohybrid Nanofibers for Wound Dressings. The burden that chronic wounds place on people and healthcare systems is significant. These skin sores are easily exposed to germs, which in turn causes inflammation and hinders the healing process.
Additionally, germs can cause an infection that prevents collagen production and re-epithelialization. Appropriate wound dressing materials, such as those made of biopolymers derived from nature, can reduce the risk of infection and hasten the healing process.
Particularly, biopolymeric nanofibrous dressings imitate the structure of the extracellular matrix while being biocompatible and largely biodegradable. Such nanofibrous dressings have a large surface area and can distribute antibiotics and antibacterial agents locally into the wound environment to reduce infection.
Antibacterial biohybrid nanofibrous wound dressings are gradually replacing antibiotic delivery systems due to the alarming growth of antibiotic-resistant microorganisms. Biopolymeric nanofibers with antibacterial nanoparticles, natural chemicals, and biofunctional agents make up this new type of wound dressings. Review and assessment of the most recent advancements in antibacterial biopolymeric nanofibrous wound dressings, notably those derived from biohybrids.
Natural polymeric nanofibers loaded with antibacterial agents, such as antimicrobial nanoparticles/ions, nature-derived chemicals, and biofunctional agents, have demonstrated a remarkable potential for replacing their traditional counterparts as an advanced class of bioactive wound dressing materials.
Such biohybrid nanofibrous wound dressings can also outperform conventional medication delivery systems, which is important given the growing concern over antibiotic-resistant bacteria.
