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In the field of biomaterials, new materials include nanofibers made of chitosan. Numerous medications, including antibiotics, chemotherapeutic agents, proteins, and analgesics for inflammatory pain, have been successfully loaded onto electrospun nanofibers, according to recent investigations.
Chitosan nanofibers have a number of exceptional qualities that make them ideal for use in important pharmaceutical applications like tissue engineering, drug delivery systems, wound dressing, and enzyme immobilisation.
There are numerous potential technological and business uses for nanofibers. They are utilised in the production of composite materials, tissue engineering, medication delivery, seed coating, cancer diagnostics, lithium-air batteries, optical sensors, air filtration, and redox-flow batteries.
Nanofibers are made from the same polymers that are used to make spherical nanoparticles, including polyvinylpyrrolidone, polylactic acid, PCL, and PLA.
Additionally, natural polymers like gelatin and chitosan may be intriguing substances to utilise in the creation of nanofibers.
Fibers with a diameter of less than 100 nm are referred to as nanofibers. This category is frequently expanded in the textile industry to include microfibers, which are fibres with a diameter of 1,000 nm or smaller.
The exterior skeleton of shellfish, such as crab, lobster, and shrimp, contains a sugar called chitosan. It is employed in the production of drugs and as medication.
A fibre protein called chitosan may limit the amount of fat and cholesterol that the body absorbs from diet. When administered to wounds, it also facilitates blood clotting.
The Global chitosan nanofiber market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
Swakit Biotech Private Limited Nature is full of chitosan, a polycationic natural polymer. As a natural polymer, chitosan has attracted considerable interest in the biomedical industry.
This review focuses on the most recent drug delivery methods as well as the use of nanotechnology for the controlled release of pharmaceuticals from chitosan nanofibers.
One of the most well-known and often used methods for creating nanofibers is electrospinning. This technique is adaptable and effective for creating continuous nanofibers.
The preparation of chitosan nanofibers, followed by a discussion of the biocompatibility and degradation of chitosan nanofibers, followed by a description of how to load the drug into the nanofibers, are the first issues highlighted by this review of chitosan nanofibers in drug delivery applications. The main uses of chitosan nanofibers in drug delivery systems will be discussed last.
