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CHLOROACETATE ALDEHYDE MARKET
INTRODUCTION
The organic compound chloroacetate aldehyde has the formula ClCH2CHO. It is an electrophilic reagent and a potentially hazardous alkylating agent, like some related compounds. Chloroacetate aldehyde is a metabolite of the antineoplastic ifos famide and is believed to be responsible for some of the toxicity observed with ifos famide.
It is also a useful intermediate in the synthesis of 2-aminothiazole, which includes the pharmaceuticals actinide, polythiazide, brotizolam, and clotiazepam.[5] Chloroacetate aldehyde is also used.
Using chloroform, toluene, or carbon tetrachloride, azeotropic distillation of the hydrate yields water-free chloroacetate aldehyde. Polyacetals are produced reversibly from anhydrous chloroacetate aldehyde. To get chloroacetate aldehyde or to completely avoid its intermediate formation, less reactive chloroacetate aldehyde derivatives could be used instead.
CHLOROACETATE ALDEHYDE MARKET SIZE AND FORECAST
The Global Chloroacetate aldehyde market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
CHLOROACETATE ALDEHYDE MARKET RECENT DEVELOPMENT AND INNOVATION
Meta board for Chloroacetate aldehyde – An azeotropic removal of water with the aid of a solvent, wherein the solvent is a halogenated solvent, is used to prepare chloroacetate aldehyde acetals of monohydric, dihydric, or higher-functionality aliphatic alcohols using the chloroacetate aldehyde acetal obtained from an aqueous chloroacetate aldehyde solution in the presence of the alcohol to be acetalized and an acid catalyst.
Chloroacetate aldehyde is a versatile precursor to numerous heterocyclic compounds because it is bifunctional. Aminothiazoles are produced when it condenses with thiourea derivatives.
As a precursor to sulfathiazole, one of the first sulfa drugs, this reaction was once crucial. The organic compound with the formula ClCH2CHO is chloroacetate aldehyde. It is an electrophilic reagent and a potentially hazardous alkylating agent, like some related compounds.
The compound is typically found in its hydrate (acetal) form, ClCH2CH(OH)2, rather than in its anhydrous form. Chloroacetate aldehyde is a useful intermediate in the synthesis of many pharmaceutical compounds, such as 2-aminothiazole. Another use involves making it easier to remove bark from tree trunks.
It is used as a Building block for heterocycles (e.g. furans’, thiazoles, thiophenes, 1,2,3-thiadizoles, pyrenes, 1,3,5-triazines) and aloes Building block for amino acids (Cysteine, Serine).
It is used in the synthesis of pharmaceuticals (e.g. Sulfathiazole, Sulfamate oxadiazines, Tolmetin etc.) and used as a Building block for pesticides (e.g. Fenfuram, Theda azurin).It plays a major role in synthesis of dyes.
