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Cinnarizine/dimenhydrinate is a fixed-dose combination drug used to treat vertigo in adults and is marketed under the trade names Cizinate and other names. It comprises dimenhydrinate and cinnarizine. It is consumed orally.
Cinnarizine develops slowly. It may take up to 4 hours after taking the tablet for the medication to start working fully. The anti-vertigo medication CINNARIZINE+DIMENHYDRINATE is used to treat the vertigo symptoms of nausea, vomiting, dizziness, and a spinning sensation.
When you experience vertigo, it might be challenging to perform daily tasks. CINNARIZINE+DIMENHYDRINATE can help. Dizziness brought on by a sudden internal or exterior spinning feeling is known as vertigo.
It gives the impression that you are moving or that your environment is whirling.The medication combination CINNARIZINE+DIMENHYDRINATE contains the calcium antagonist Cinnarizine and the diuretic dimenhydrinate (antihistamine).
The blood flow in the ear is improved because cinnamon arizona stops the blood vessels in the ear from constricting. By preventing the action of the chemical messenger histamine, dimenhydrinate prevents issues with loss of balance. When used as a pair, CINNARIZINE+DIMENHYDRINATE aids in easing vertigo symptoms.
The Global cinnarizine dimenhydrinate market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
cinnarizine There are numerous reasons for vertigo. These can be central, like cerebral ischaemia, or peripheral, like labyrinthitis. They can even be a combination of the two.
Although the cause of vertigo should be treated, the symptom has been treated using a variety of medications. Antihistamines, anticholinergics, and antiemetics are a few of them.
Two antihistamines are present in the combination product. Dopamine D2 receptors and histamine H1 and H4 receptors are both blocked by cinnarizine.
Calcium channels may also be blocked by it. A salt of diphenhydramine and chlorotheophylline is known as dimenhydrinate. It can reach the brain and inhibit both muscarinic acetylcholine receptors and histamine H1 receptors.
Cinnarizine and dimenhydrinate working together will consequently have both peripheral and central effects.Dimenhydrinate releases diphenhydramine after oral ingestion.
Peak plasma concentrations of diphenhydramine and cinnarizine are obtained in 2-4 hours following fast absorption. that are primarily metabolised in the liver by cytochrome P450 (CYP) 2D6.
It has the potential to interact with other medications metabolised by CYP2D6, including beta blockers and antidepressants.
