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Clomipramine is a tricyclic antidepressant that is marketed under the brand names Anafranil and others (TCA). Obsessive-compulsive disorder, panic disorder, severe depressive disorder, and chronic pain are all treated with it.
In people under the age of 25, it might raise their risk of suicide. Most people take it orally. Additionally, it has been used to treat early ejaculation. Dry mouth, constipation, lack of appetite, tiredness, weight gain, sexual dysfunction, and difficulty peeing are typical adverse effects.
Seizures, mania, liver issues, and an increased risk of suicidal behaviour in people under the age of 25 are considered serious adverse effects. If abruptly discontinued, a withdrawal syndrome with headaches, perspiration, and lightheadedness may develop.
If using it while pregnant is safe is unknown. Its mode of action.Doctors typically consider clomipramine (CMI) as a treatment for obsessive-compulsive disorder (OCD). However, it has dual SNRI effect and is a powerful antidepressant (see tables of comparative receptor affinity data below and my TCA review).
The Global CLOMIPRAMINE market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Both a brand-name and a generic version of the oral capsule medication clomipramine are offered. Anafranil is a brand name. There is only one oral capsule form of clomipramine.
Obsessive-compulsive disorder is treated with clomipramine oral capsules in order to reduce excessive and recurrent urges, thoughts, and ideas. Clomipramine modified release tablets, Anafranil SR 75mg, were discontinued in 2015. Team for Optimising Medicines.
Further advice will be provided regarding potential alternate treatment alternatives and switch strategies4 if the 25mg and 50mg strengths become unavailable.Tricyclic antidepressants include clomipramine (TCA).
It is believed to function in the brain through boosting serotonin’s action. Only a prescription from your doctor is required to purchase this medication. A tricyclic antidepressant called clomipramine is used to treat obsessive-compulsive disorder.
Clomipramine is a rare cause of clinically evident acute liver injury and can result in moderate, temporary increases of blood enzymes.A tricyclic antidepressant called clomipramine is used to treat obsessive-compulsive disorder. Clomipramine is a rare cause of clinically evident acute liver injury and can result in moderate, temporary increases of blood enzymes.