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Colchicine is a medication used to treat gout and Behçet’s disease. In gout, it is less preferred to NSAIDs or steroids. Other uses for colchicine include the management of pericarditis and familial Mediterranean fever. Colchicine is taken by mouth.
Colchicine has a narrow therapeutic index, so overdosing is a significant risk. Common side effects of colchicine include gastrointestinal upset, particularly at high doses.
Severe side effects may include low blood cells and rhabdomyolysis, and the medication can be deadly in overdose. Whether colchicine is safe for use during pregnancy is unclear, but its use during breastfeeding appears to be safe. Colchicine works by decreasing inflammation via multiple mechanisms.
Colchicine, in the form of the autumn crocus (Colchicum autumnale), has been used as early as one thousand five hundred BC to treat joint swelling. It was approved for medical use in the United States.
It is available as a generic medication. Colchicine is widely used in plant breeding for inducing polyploidy, where the number of chromosomes in plant cells are doubled. This frequently results in larger, hardier, faster-growing, and in general more desirable plants than the normally diploid parents.
The Global Colchicine market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
Laurus Lab COLCHICINE – COLCHICINEis an anti-inflammatory agent and belongs to the class of anti-gout agents. It is used in the treatment and prevention of acute attacks or flare-ups of gout. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints.
It is characterized by intense pain and swelling in the affected joints. COLCHICINE decreases pain, swelling, and inflammation. It also prevents sudden attacks of pain caused by acute gout.COLCHICINE contains Colchicine. It works by reducing the inflammation caused by crystals of uric acid in your joints. This helps to reduce pain.
COLCHICINE may interact with lipid-lowering medications such as atorvastatin and rosuvastatin, the medicine used to treat heart disorders such as digoxin, nonsteroidal anti-inflammatory drugs (NSAIDs) such as naproxen and ibuprofen.
Anti-fungal drugs such as ketoconazole and itraconazole, drugs used to treat alcoholism such as disulfiram, antibiotics such as clarithromycin, and antidepressants such as nefazodone.
