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Last Updated: Apr 25, 2025 | Study Period: 2024-2030
Conjugated estrogens, also known as conjugated equine estrogens, are an estrogen drug used in menopausal hormone therapy as well as for a number of other reasons. It is marketed under the trade name Premarin among others.
A medication called conjugated estrogens is made up of several estrogen hormones. It is used to treat mild to severe hot flashes, vaginal changes, and other signs of menopause or low estrogen levels (hypoestrogenism). The risk of having a disease that can result in uterine cancer may be increased by conjugated estrogens. cancer.
The Global Conjugated Estrogen Market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Conjugated estrogens are a mix of estrogens that are used in postmenopausal osteoporosis treatment as well as in the treatment of various cancers and in estrogen replacement therapy for menopause and hypoestrogenism. treatment for moderate to severe menopausal vasomotor symptoms.
treatment for mild to moderate vulvar and vaginal atrophy brought on by menopause. Therapy for hypoestrogenism brought on by castration, hypogonadism, or primary ovarian failure. breast cancer palliative care for carefully chosen patients with metastatic disease. palliative care for prostate cancer caused by androgen dependence. postmenopausal osteoporosis prevention treatment.
The conjugated estrogens function similarly to the physiological estrogen in that they bind agonistically to the estrogen receptors alpha and beta. The number and ratio of estrogen receptors varies depending on the tissue, and as a result, conjugated estrogens have a very wide range of activity.
In order to inhibit the production of gonadotropin-releasing hormone, follicle-stimulating hormone, and luteinizing hormone, the activity produced by conjugated estrogens is driven by an increase in the synthesis of DNA, RNA, and different proteins in sensitive tissues.
Many distinct metabolic pathways are used to process the conjugated estrogens. The cytochrome isoenzyme CYP3A4. drives one of the metabolic routes for conjugated estrogens.
The conjugated estrogens, on the other hand, can also be broken down by a dynamic balance of metabolic interconversion and sulphate conjugation. 17-beta-estradiol is converted to estrone and then to estriol, which in turn drives some of the main metabolic processes of the conjugated estrogens.
The blood acts as a circulating reservoir for the production of new estrogens by retaining some of the supplied conjugated estrogens as sulphate conjugates.
Sl no | Topic |
1 | Market Segmentation |
2 | Scope of the report |
3 | Abbreviations |
4 | Research Methodology |
5 | Executive Summary |
6 | Introduction |
7 | Insights from Industry stakeholders |
8 | Cost breakdown of Product by sub-components and average profit margin |
9 | Disruptive innovation in the Industry |
10 | Technology trends in the Industry |
11 | Consumer trends in the industry |
12 | Recent Production Milestones |
13 | Component Manufacturing in US, EU and China |
14 | COVID-19 impact on overall market |
15 | COVID-19 impact on Production of components |
16 | COVID-19 impact on Point of sale |
17 | Market Segmentation, Dynamics and Forecast by Geography, 2024-2030 |
18 | Market Segmentation, Dynamics and Forecast by Product Type, 2024-2030 |
19 | Market Segmentation, Dynamics and Forecast by Application, 2024-2030 |
20 | Market Segmentation, Dynamics and Forecast by End use, 2024-2030 |
21 | Product installation rate by OEM, 2023 |
22 | Incline/Decline in Average B-2-B selling price in past 5 years |
23 | Competition from substitute products |
24 | Gross margin and average profitability of suppliers |
25 | New product development in past 12 months |
26 | M&A in past 12 months |
27 | Growth strategy of leading players |
28 | Market share of vendors, 2023 |
29 | Company Profiles |
30 | Unmet needs and opportunity for new suppliers |
31 | Conclusion |
32 | Appendix |