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A flavonoid called diosmin is most frequently found in citrus fruits. Plant components known as flavonoids have antioxidant qualities that guard your body against inflammation and unstable molecules known as free radicals ( 1 , 2 ). Diosmin was initially discovered in figwort plants (Scrophularia nodosa L.)
In persons with venous insufficiency, a condition where blood flow is compromised, it is thought to aid in reducing inflammation and restoring regular blood flow.
Another flavonoid known as hesperidin, which is also present in citrus fruits, particularly orange rinds, is the source of diosmin, which is frequently used (2Trusted Source).
Micronized purified flavonoid fraction (MPFF), a class of flavonoids that comprises the flavonoids disomentin, hesperidin, linarin, and isorhoifolin, is frequently mixed with diosmin.
Hemorrhoids and chronic venous insufficiency are two blood vessel problems that are most commonly treated with diosmin (CVI). While CVI refers to swollen, obstructed veins in the legs, haemorrhoids are enlarged veins close to the anus.
Diosmin side effects are uncommon but might include stomach discomfort, diarrhoea, headaches, lightheadedness, hives, skin rash, muscle soreness, and – in extreme situations — irregular heartbeat.
Global diosmin flavonoid market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Up to 80% of the general population can develop chronic venous disease (CVD), which is a frequent medical problem.
Clinical manifestations can include minor to more serious signs and symptoms that affect a patient’s quality of life (QoL) in some way.
Venoactive medications, like diosmin, are frequently employed in the symptomatic therapy across all clinical stages,the efficiency of a newly developed diosmin in treating symptoms and enhancing QoL in CVD patients.
Diosmin is a venoactive medication (VAD) that improves quality of life and CVD symptoms (QoL).
Due to its specific phlebotonic action on the venous wall and its anti-inflammatory and antioxidant properties related to the inhibition of a number of chemical mediators of inflammation (cytokines, metalloproteases, histamine, serotonin, etc.), diosmin, a naturally occurring flavonoid, is regarded as a vascular protectant agent.
The two major goals of modern pathology treatments, which are mostly based on the actions of citrus bioflavonoids, are to treat the symptoms and slow the evolution of the illness in order to avoid potential problems.
