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Labetalol is a medication used to treat high blood pressure and in long term management of angina. This includes essential hypertension, hypertensive emergencies, and hypertension of pregnancy. In essential hypertension it is generally less preferred than a number of other blood pressure medications. It can be given by mouth or by injection into a vein.
Common side effects include low blood pressure with standing, dizziness, feeling tired, and nausea. Serious side effects may include low blood pressure, liver problems, heart failure, and bronchospasm. Use appears safe in the latter part of pregnancy and it is not expected to cause problems during breastfeeding. It works by blocking the activation of β-receptors and α-receptors.
Labetalol is effective in the management of hypertensive emergencies, postoperative hypertension, pheochromocytoma-associated hypertension, and rebound hypertension from beta blocker withdrawal. It has a particular indication in the treatment of pregnancy-induced hypertension which is commonly associated with pre-eclampsia.
It is also used as an alternative in the treatment of severe hypertension. Labetalol is contraindicated in people with overt cardiac failure, greater-than-first-degree heart block, severe bradycardia, cardiogenic shock, severe hypotension, anyone with a history of obstructive airway disease including asthma, and those with hypersensitivity to the drug.
The Global Labetalol Market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
CIPLA Labetalol – LABETALOL belongs to the blood pressure-lowering medications called ‘beta-blocker’ used to treat hypertension (high blood pressure). Additionally, LABETALOL is used to control high blood pressure in pregnancy and during anaesthesia.
High blood pressure is a condition in which the blood exerts elevated pressure on blood vessel walls, leading to various cardiovascular complications like the risk of heart attack and stroke in the future.
LABETALOL contains ‘labetalol’ that works by blocking the receptors in the cardiovascular system, this helps decrease the blood pressure in the blood vessels.
LABETALOL helps the heart to beat slower with less force. It also relaxes and widens the blood vessels, this makes it easier for the heart to pump blood to all parts of the body. Thereby, helps in lowering the raised blood pressure and reducing the overload of the heart.