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Fixing, staining, dehydrating, or decalcifying tissue samples for analysis is done with a tissue processor. The process of making fixed tissues suitable for embedding in a supportive medium like paraffin is known as tissue processing.
It consists of three distinct steps: clearing, infiltration, and dehydration. Ethanol is the alcohol most frequently utilized in tissue processing.
This alcohol is mostly used to treat tissues from animals and plants. N-butanol shrinks and hardens less than ethanol, but it takes longer to dissolve in water and paraffin wax due to its poor miscibility. DONATELLO is a closed-circuit tissue processor that works automatically. Histological specimens utilize it.
There are numerous steps involved in preparing fresh tissue samples for use under a microscope, including fixation and processing, embedding and microtomy, deparaffinization and staining, and coverslipping.
The two primary types of processors are: the tissue-transfer machines, also known as “dip and dunk” machines, in which specimens are moved from one container to another in order to be processed.
The fluid-transfer machines, also known as “enclosed” machines, hold specimens in a single process chamber or retort, and fluids are pumped in and out as needed.
The Global Tissue Processing Machine Market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
The HistoCore PEGASUS Plus* is a new compact tissue processor from Leica Biosystems with two retorts. Their renowned technology will be available to medium-sized laboratories for the first time, allowing them to improve histopathology workflows.
Now that multiple protocols can be run simultaneously on a single instrument, laboratories of a medioeval size will be able to meet their unique workflow requirements and cut down on unnecessary hands-on time.
When compared to a standard 300-cassette single-retort tissue processor, the capacity of the HistoCore PEGASUS Plus’s dual retorts is increased by 33%.
In addition to incorporating Leica’s ground-breaking integrated track and trace technology, the HistoCore I-Scan, the HistoCore PEGASUS Plus builds on more than 15 years of experience with the larger HistoCore PELORIS system. With high confidence in the quality of the results, laboratories are able to record and store individual cassette information, user interactions, and reagent levels.