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Ultrasonic homogenizers are commonly used to disrupt cells and tissues via sound waves and the cavitation that they cause.
The homogenizer tip vibrates rapidly, creating bubbles that form and collapse. This action tears apart any cells or particles in the solution.
A homogenizer works by breaking or subdividing the dispersed components into smaller particles and then distributing them evenly throughout the mixture.
The action created by the homogenizer continuously disrupts the formation of large particles due to immiscibility and precipitation.
An ultrasonic homogenizer consists of: A power generator and control ; A transducer or converter to change electric energy into high-frequency mechanical motion ; A probe or “horn,” typically made of titanium, which vibrates rapidly and longitudinally to transmit energy to the sample.
Its major applications are to Create emulsions ; Disperse nanoparticles ; Reduce the size of suspended particles ; Break apart cells and subcellular structures in suspension ; Shear DNA (beneficial for some applications).
Basically, an ultrasonic homogenizer has a tip which very rapidly vibrates, causing bubbles in the surrounding solution to rapidly form and collapse. This creates shear and shock waves which tear apart cells and particles.
The Global Ultrasonic Homogenizer market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
LABTRON Ultrasonic homogenizer (Sonicator) LUHS-A17 – Ultrasonic homogenizer (Sonicator) LUHS-A17 is a homogenizer with 500 to 5000 ml disruption capacity.
With 19.5 to 20.5 KHz operation frequency it is used for disruption of cells, for emulsification, homogenization, cleaning, and preparation of nanomaterials, foaming and dispersion of chemicals.
It is majorly Used in nanomaterials preparations, tissue culture processing, biotechnology, chemistry, pharmacy for processing, homogenization, sonication of test material.
Key features are Large LCD backlit display ; 2400 W ultrasonic power ; Microprocessor controlled system ; Automatic Frequency tracking ; Pulse and continuous operations ; Up to 0.1 seconds accuracy for ultrasonic time, gap, total time.
Homogenizers are used to blend chemical or biological samples. This often includes lysing of cells to form one homogenous suspension.
With the addition of a homogenizer instrument to your laboratory, the necessity of a mortar and pestle and brute force are eliminated.
Microfluidizer Technology,Unmatched standards for particle size reduction, cell disruption, and homogeneous nanoemulsions.
Fluid pressure is transformed to high shear forces more effectively and reliably by microfluidizer technology than by competing technologies.
Microfluidizer homogenizers guarantee that 100% of a given material receives the same treatment by maintaining consistent pressure.
Due to the inherent differences between Microfluidizer and high-pressure valve homogenization technologies, significantly less process energy is transferred to heat. This not only saves energy, but also helps to avoid temperature impacts from changing the physicochemical properties of any fragile materials being processed.
It’s no surprise, then, that process engineers in industries ranging from pharmaceuticals to vaccines to fine chemicals to biotechnology, cosmetics, food processing, and energy have discovered that Microfluidics is superior technology for the efficient creation of nanoparticles and nanoemulsions, among other applications.
Despite the fact that some of these applications can also be accomplished with traditional homogenizers, Microfluidizer processors produce outcomes that are superior in terms of higher particle size reductions, tighter particle size distributions, repeatability, and smooth scaling.
The architecture of the unique fixed-geometry Interaction Chamber, which is unique to the Microfluidizer technology, is the secret to its astounding efficiency.
Materials undergo high shear forces when fluids are driven through the special Interaction Chamber at constant pressures and set temperatures, producing precisely regulated particle size reductions and remarkably narrow particle size distribution curves.
Customers have the option to utilise less energy to reach particle size reduction objectives, which are frequently lower than those feasible with standard homogenizer technologies, thanks to the ability to alter the amount of shearing.
It goes without saying that although developing an efficient process during the research and development stage is one thing, trying to scale it up to the full production run capacity is frequently quite another.
Customers may avoid this frequent potential blunder by using Microfluidics’ assured scale-up success.
Regardless of where you are in the development process for your droplet microfluidics applications, you can rely on Microfluidizer technology to deliver the particle size reductions you require, more efficiently and more consistently.
This is true whether using carefully engineered machines to achieve cell disruption, nanoemulsions, nanoencapsulation, liposomes, or some other cutting-edge application.
