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A cell-based biosensor is a device that uses living cells to detect the presence of specific compounds or changes in the environment.
These biosensors function by taking advantage of the natural qualities of cells, such as their ability to respond to specific stimuli or their synthesis of specific chemicals, to detect and analyze diverse analytes.
A signal transduction system is utilized to transform the reaction of the cells to the target chemical into a quantifiable output signal in a conventional cell-based biosensor, which consists of living cells connected to a substrate or incorporated into a matrix.
The output signal can be read using many types of detecting devices, such as optical, electrochemical, or magnetic sensors.
Cell-based biosensors offer a wide range of applications, including environmental monitoring, medical diagnostics, drug development, and food safety testing.
They are particularly useful for detecting substances that are difficult to detect using traditional methods or for monitoring the impact of medications or other compounds on living cells in real time.
The Global Cell-Based Biosensor Market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Better biosensor technology developed by a team at Rutgers could pave the way for secure stem cell therapies for the treatment of Alzheimer’s, Parkinson’s, and other neurological disorders.
According to a study published in the journal Nano Letters, the technology, which includes a special graphene and gold-based platform and cutting-edge imaging, monitors the fate of stem cells by detecting the genetic material (RNA) necessary in converting such cells into brain cells (neurons).
Numerous cell types can be developed from stem cells. Because diseased cells in neurological illnesses like Alzheimer’s, Parkinson’s, stroke, and spinal cord injury need to be replaced or repaired, stem cell therapy holds promise as a regenerative treatment.
But before stem cells can be used in treatments, characterizing them and deciding on their fate must be worked out. Tumour growth and unchecked stem cell transformation continue to be major obstacles.
The group is confident that a variety of applications can profit from the technology. Lee’s team is working to create inexpensive, quick, and precise sensing systems to help with stem cell therapy for neurological illnesses.
According to the National Institutes of Health, stem cells may develop into a regenerative source of replacement cells and tissues to treat conditions like macular degeneration, spinal cord injury, stroke, burns, heart disease, diabetes, osteoarthritis, and rheumatoid arthritis.
