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Intraoperative fluorescence imaging is one technique. The boundary between the tumour and normal brain may now be seen in real time with this technique, which is not possible with a traditional surgical microscope when it is lit by white light.
The viewing of fluorescent proteins or dyes as markers for molecular structures or processes is known as fluorescence imaging. It makes a variety of experimental findings possible, such as where and how proteins are expressed, where and how genes are expressed in cells, and how molecules interact in tissues.
In a fluorescent microscope, a sample is marked with a fluorophore, which is then illuminated by strong light (excitation light), producing fluorescence (emission light). As a result of the fluorophore’s brightly coloured light emission, samples are sharply contrasted against the black backdrop in this way.
Orthopaedic surgeons use intraoperative fluoroscopy as a vital tool for treating fractures. Based on a succession of pictures delivered to a display, it enables the surgeon to assess the static or dynamic images of the structure of interest.
The Global Intraoperative fluorescence imaging market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
140 international specialists agree on the use of intraoperative fluorescence imaging in several surgical specialties.
There is a lot of variation in how and when intraoperative fluorescence imaging combined with indocyanine green dye is utilised, and there are no published consensus recommendations. This is despite the fact that the data supporting its use is exponentially rising.
performed Delphi surveys of international specialists on the use of intraoperative fluorescence imaging for 6 different surgical scenarios, including thyroid and parathyroid resections, colorectal surgery, lymphedema, gastric cancer, and plastic surgery.
Seven Delphi studies were carried out by the International Society for Fluorescence-Guided Surgery (ISFGS). The first study, which was conducted among 19 attendees of the ISFGS Annual Scientific Meeting in Frankfurt, Germany, looked at general intraoperative fluorescence imaging (FI) difficulties, and it has already been published.
Among its numerous conclusions were the following: giving indocyanine green (ICG) dye and utilising fluorescence are both extremely safe procedures; there was 100% agreement that the role of intraoperative FI will rise over the next decade, both in clinical practise and research.
