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Last Updated: Apr 25, 2025 | Study Period: 2024-2030
Severe hypothyroidism, which causes hypothermia, diminished mental status, and other symptoms related to slowed organ function, is known as myxedema coma.It is a life-threatening medical emergency. The body's temperature can decrease significantly in cold conditions. Most often, myxedema coma occurs in the winterevent that brings rain. Examine the patient for signs of exposure to the cold, infection, medication (diuretics, tranquillisers, sedatives, and analgesics), trauma, stroke, heart failure, and gastrointestinal bleeding.
Myxedema is frequently diagnosable only based on clinical evidence. Weakness, aversion to the cold, mental and physical slowness, dry skin, recognizable facial features, and raspy voice are frequent symptoms.The results of the tests for free thyroxine index and total serum thyroxine usually corroborate the diagnosis. A rare medical condition known as myxedema coma is the most extreme form of severe hypothyroidism.
In the winter and more frequently in the elderly, this is typically brought on by stressful situations such infections and cardiac infarction. 100 mg of hydrocortisone were administered intravenously every eight hours until suspected adrenal insufficiency was ruled out.TSH stands for thyroid-stimulating hormone; T4 for thyroxine. In elderly patients, individuals with lower weights, and patients who are at risk for cardiac problems, the lower end of the dose ranges is preferred.
The Global myxedema coma market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Adults diagnosed with myxedema coma have increased mortality risk, longer hospital stay. Adults with hypothyroidism who are admitted to the hospital and are found to have myxedema coma die more frequently and stay in the hospital longer. Retrospective examination of inpatient hospital admissions to non-federal hospitals in the United States was done by Angell and colleagues. Adults who were 18 years of age or older and had hypothyroidism or myxedema coma as their major diagnosis were included.
The National Inpatient Sample database was used to acquire data on demographics, mortality, hospitalisation duration, and expenses. At the AACE Annual Scientific and Clinical Conference, the findings were presented. The investigation comprised 18,635 hypothyroid people, of which 13.4% had myxedema coma as a diagnosis. Myxedema coma was more frequently identified in older persons, those with public health insurance, and homeless adults.
Adults were more likely to develop myxedema coma if they had previously been treated for septicemia, an acute myocardial infarction, or adrenal insufficiency. Adults with myxedema coma were more likely than non-patients to require a vasopressor, go into cardiogenic shock, develop acute heart failure, or have acute respiratory failure (P .001 for all). Individuals with myxedema coma had an annual death rate between 5.1% and 9.3% over the study period, compared to 0.5% to 0.9% for individuals with hypothyroidism but no myxedema coma.
Although the fatality rate among individuals with myxedema coma was higher, it was still lower than that shown in earlier research, according to Angell. Adults with myxedema coma spent an average of 8.28 to 10.4 days in the hospital compared to adults without the condition spending 4.36 to 4.86 days there. Adults with myxedema coma saw mean hospitalisation expenditures that ranged from $86,511 to $92,415âmore than twice as expensive.
The average cost of hospitalisation for adults with hypothyroidism but no myxedema coma ranged from $34,025 to $42,730. Future research, according to Angell, analysing patient-level clinical data are required to more effectively diagnose and treat myxedema coma.
Company | Product | Year | Description |
Prolevi Bio | SR LT3 | 2023 | It releases hormones based on the body's circadian rhythm to treat hypothyroidism. |
Azurity Pharmaceuticals, Inc. | Adthyza | 2023 | It is a natural preparation derived from porcine thyroid glands and may have a characteristic odor. |
Sl no | Topic |
1 | Market Segmentation |
2 | Scope of the report |
3 | Abbreviations |
4 | Research Methodology |
5 | Executive Summary |
6 | Introduction |
7 | Insights from Industry stakeholders |
8 | Cost breakdown of Product by sub-components and average profit margin |
9 | Disruptive innovation in the Industry |
10 | Technology trends in the Industry |
11 | Consumer trends in the industry |
12 | Recent Production Milestones |
13 | Component Manufacturing in US, EU and China |
14 | COVID-19 impact on overall market |
15 | COVID-19 impact on Production of components |
16 | COVID-19 impact on Point of sale |
17 | Market Segmentation, Dynamics and Forecast by Geography, 2023-2030 |
18 | Market Segmentation, Dynamics and Forecast by Product Type, 2023-2030 |
19 | Market Segmentation, Dynamics and Forecast by Application, 2023-2030 |
20 | Market Segmentation, Dynamics and Forecast by End use, 2023-2030 |
21 | Product installation rate by OEM, 2023 |
22 | Incline/Decline in Average B-2-B selling price in past 5 years |
23 | Competition from substitute products |
24 | Gross margin and average profitability of suppliers |
25 | New product development in past 12 months |
26 | M&A in past 12 months |
27 | Growth strategy of leading players |
28 | Market share of vendors, 2023 |
29 | Company Profiles |
30 | Unmet needs and opportunity for new suppliers |
31 | Conclusion |
32 | Appendix |