NEUROVASCULAR STENT RETRIEVERS MARKET

INTRODUCTION

The Advanced Neurovascular Access (ANA) thrombectomy system is a revolutionary stroke thrombectomy device that consists of a self-expanding funnel meant to prevent clot fragmentation by limiting flow locally while becoming as broad as the lodging artery.

Once implanted, the ANA device uses distal aspiration in conjunction with a stent retriever to mobilize the clot into the funnel, where it stays captured until extraction.

SOLONDA (Solitaire in Combination With the Anaconda Catheter System) was a prospective, open, single-arm, multicenter study with blinded main outcome evaluation by an independent core lab.

Patients with anterior circulation artery blockage who were hospitalized within 8 hours of the beginning of symptoms were eligible.

With three passes of the catheter, the primary end objective was effective reperfusion (modified Thrombolysis in Cerebral Infarction score 2b-3)

Anaconda Biomed's Advanced Neurovascular Access (ANA device or ANA catheter system, Barcelona, Spain) is a new stroke thrombectomy device that includes a self-expanding funnel component designed to reduce side effects caused by clot fragmentation by locally restricting blood flow while becoming as wide as the diameter of the lodging artery. 

Once in place, the ANA device uses distal aspiration in conjunction with a stent retriever (SR) to mobilize the clot into the funnel, where it stays caught and protected until extraction.

The ANA device performed better than the SR in in vitro phantom and swine models of human neurovascular architecture when combined with a distal aspiration catheter or a balloon guiding catheter.A preliminary first in human report revealed promising findings in terms of safety and effectiveness.

The ANA is a thrombectomy device that consists of two coaxial catheters: the funnel catheter and the delivery catheter, both of which are built of variable stiffness parts.

The funnel catheter is made out of a braided self-expanding metallic construction that is completely wrapped with a highly flexible polymer. 

Its purpose is to limit blood flow locally during the intervention, and it can offer successful aspiration as a supplementary mechanism when used in conjunction with an SR.

The delivery catheter is the device's outer catheter that navigates until it reaches the target vessel. In all patients, a microcatheter was advanced through a micro guidewire to the clot after the guide catheter was inserted at the level of the internal carotid artery in a triaxial setting. After that, the ANA catheter system was withdrawn.

The ANA catheter system was then withdrawn and positioned as close to the proximal part of the clot as feasible (terminal internal carotid artery or middle cerebral artery), and the funnel was deployed to limit flow locally.

The funnel then self-expands to the diameter of the artery. The microcatheter was then pushed into the occlusion site, and the SR (Medtronic Solitaire family) was deployed as normal.

AThe SOLONDA trial (Solitaire in Combination With the Anaconda Catheter System) aims to evaluate the safety and performance of the ANA catheter system combined with an SR in acute ischemic stroke.

Stent retrievers are momentarily extended into the body of a thrombus after being inserted in an obstructed artery.

This treatment recanalized the artery, allowing reperfusion of ischemic areas and partially entangling the thrombus within the stent. The stent is retracted during thrombolysis.

This stage, the microcatheter was removed completely to expand the aspiration lumen, and manual aspiration was performed using the ANA funnel catheter.

When the distal ends of the SR and ANA funnel catheters were aligned, the ANA and SR were both taken out at the same time. The clot was retained during the evacuation via the guiding catheter.

NEUROVASCULAR STENT RETRIEVERS MARKET SIZE AND FORECAST

The Global Neurovascular Stent Retrievers Market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.

NEUROVASCULAR STENT RETRIEVERS MARKETMARKET DYNAMICS

The NeuroVasc Envi-SR Randomised Controlled Trial is investigating the NeuroVasc ENVI-SR, a stent-retriever intended for the treatment of acute ischemic stroke.

The procedure is intended to minimize impairment in stroke patients with major artery blockage by eliminating blood clots.

The study is a prospective, multinational, randomized, parallel group-controlled, blinded, non-inferiority trial designed to examine and compare clinical outcomes of patients treated for acute ischemic stroke as measured by the Modified Rankin Scale (mRS) at days post treatment, as well as related performance characteristics of the NeuroVasc ENVI-SR and concurrent parallel Control Devices currently cleared by the U.S. Food and Drug Administration (FDA) for treatment of ischemic stroke.

The number of strokes is increasing as the population ages. Stroke is the world's second biggest cause of mortality, according to the World Health Organisation.

An acute ischemic stroke occurs when blood flow to a portion of the brain is cut off or decreased, preventing brain tissue from receiving oxygen and nutrients.

When this occurs, brain cells begin to die within minutes, and immediate treatment is critical.

Early intervention can help to decrease brain damage and adverse effects including physical impairment and death.The ENVI RCT study is the first prospective clinical trial in ischemic stroke.

It is an international, multicenter, randomized, controlled clinical trial to evaluate the efficacy and safety of the NeuroVasc Envi-SR mechanical thrombectomy device for blood flow restoration in ischemic stroke.

NEUROVASCULAR STENT RETRIEVERS MARKETCOMPANY PROFILE

• BMJ
• Medtronic
• Stryker
• Sutter Health
• Frontiers

NEUROVASCULAR STENT RETRIEVERS MARKETTHIS REPORT WILL ANSWER FOLLOWING QUESTIONS

• How many   Neurovascular Stent Retrievers   are manufactured per annum globally? Who are the sub-component suppliers in different regions?
• Cost breakup of a Global  Neurovascular Stent Retrievers   and key vendor selection criteria
• Where are the  Neurovascular Stent Retrievers  manufactured? What is the average margin per unit?
• Market share of Global  Neurovascular Stent Retrievers   market  manufacturers and their upcoming products
• Cost advantage for OEMs who manufacture Global  Neurovascular Stent Retrievers   in-house
• 5 key predictions for next 5 years in Global  Neurovascular Stent Retrievers   market
• Average B-2-B   Neurovascular Stent Retrievers market price in all segments
• Latest trends in   Neurovascular Stent Retrievers market, by every market segment
• The market size (both volume and value) of the   Neurovascular Stent Retrievers   market in 2024-2030 and every year in between?
• Production breakup of   Neurovascular Stent Retrievers   market, by suppliers and their OEM relationship