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A robot is a machine that can automatically complete a complex series of tasks, especially one that can be programmed by a computer. Robots can be controlled internally or externally by use of a control mechanism.
Although some robots are built to resemble humans, most robots are task-performing machines that place a greater emphasis on bare functionality than on expressive aesthetics.
Robots are frequently utilised in mass production of consumer and industrial items, assembly and packaging of those commodities, transportation, earth and space exploration, surgery, armament, and laboratory research.
CHiP is a perceptive robot dog. CHiP is always attentive and prepared to play thanks to its cutting-edge sensors and intelligent accessories.
The Global Robot-on-Chip market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
A robotic platform for fluidically-linked human body-on-chips.A ‘Interrogator’ device that automates the culture, perfusion, medium addition, fluidic linking, sample collection, and in situ microscopic imaging of up to 10 Organ Chips inside a typical tissue culture incubator using liquid-handling robotics, a customised software programme, and an integrated mobile microscope.
When 8 different vascularized, 2-channel Organ Chips (intestine, liver, kidney, heart, lung, skin, blood-brain barrier (BBB), and brain) were intermittently fluidically coupled through their medium reservoirs and endothelium-lined vascular channels using a common blood substitute medium, the automated Interrogator platform maintained their viability and organ-specific functions.
Vascularized human Organ Chips are in vitro vascular perfused microfluidic cell culture devices that replicate the multicellular architecture, tissue-tissue interfaces, and relevant physical microenvironments of key functional units of living organs.
They contain separate vascular and parenchymal compartments lined by living human organ-specific cells.
The pursuit of time-course analyses of human Organ Chip models and fluidically linked, multi-organ HuBoC systems that recapitulate organ-level functions to facilitate studies of drug pharmacokinetics and pharmacodynamics (PK/PD) in vitro is motivated by the growing recognition that animal models do not effectively predict drug responses in humans and the corresponding increase in demand for in vitro human toxicity and efficacy testing.
A physiologically based multi-compartmental reduced order (MCRO) in silico model of the experimental system derived from spatio-temporal transport equations and experimental data was used to accurately predict the quantitative distributions of an inulin tracer that was perfused through the fluidic network of the multi-organ Human Body-on-Chips (HuBoC) system.
Future HuBoc experiments and in vitro pharmacokinetics (PK) study should be made easier by this automated culture platform’s ability to repeatedly sample both the vascular and interstitial compartments without affecting fluidic coupling and perform non-invasive imaging of cells within human Organ Chips.
