USA Knee Replacement Market Size, Share, Trends and Forecasts 2031

Key Findings

• The USA Knee Replacement Market is expanding as aging demographics, obesity prevalence, and earlier surgical intervention increase procedure volumes in USA.

• Cementless fixation, patient-specific instrumentation, and robotic‐assisted alignment are improving implant longevity and functional outcomes in USA.

• Outpatient and short‐stay pathways at ASCs are rising, supported by perioperative ERAS protocols and regional anesthesia adoption in USA.

• Advanced bearing materials and kinematics-matched designs are reducing wear, improving stability, and enabling faster rehab in USA.

• Bundled payments and value-based contracts are accelerating standardization of implants, disposables, and post-acute care networks in USA.

• Digital planning, intraoperative analytics, and remote monitoring are enhancing surgical precision and rehabilitative adherence in USA.

• Revision burden is growing with the expanding installed base, heightening demand for constraint options and augments in USA.

• Supply resilience for cements, trays, and sterile kits remains a procurement priority amid fluctuating global logistics in USA.

USA Knee Replacement Market Size And Forecast

The USA Knee Replacement Market is projected to grow from USD 11.2 billion in 2025 to USD 15.9 billion by 2031, at a CAGR of 5.9%. Growth is underpinned by rising osteoarthritis incidence, earlier access to surgery, and technology diffusion—navigation, robotics, and advanced bearings—that improve accuracy and satisfaction. Procedure site-of-care continues shifting toward ASCs where payer incentives and ERAS pathways compress length of stay. Vendors offering comprehensive ecosystems—implants, robotics, planning software, and patient engagement tools—capture share via integrated value propositions. As revision volumes rise, systems with modular augments and constraint versatility see elevated demand in USA.

Knee replacement (total and partial) restores joint function and reduces pain in end-stage osteoarthritis, inflammatory arthropathies, and post-traumatic degeneration. In USA, the continuum spans conservative care to primary TKA/UKA and complex revision, supported by perioperative optimization, regional anesthesia, and standardized rehab. Technology adoption focuses on component alignment, soft-tissue balancing, and personalized kinematics using navigation, robotics, and patient-specific guides. Procurement emphasizes survivorship data, instrument efficiency, and sterilization logistics, while payers drive bundled episodes and post-acute steering. Increasingly, digital planning and remote monitoring link prehab through rehab, enabling data-rich quality programs across health systems in USA.

Future Outlook

By 2031, USA will see mainstream robotic and imageless navigation with data-driven ligament balancing and intraoperative kinematic targets tailored to phenotype. Cementless fixation with porous, biologically active surfaces will gain share in younger and high-demand cohorts, while crosslinked, oxidation-resistant bearings extend durability. Outpatient pathways will dominate suitable primaries, supported by predictive risk scoring and virtual rehab that shortens recovery timelines. Revision workflows will benefit from 3D-printed augments and cones, improving bone preservation and stability. Vendors that align implant portfolios with robotics, planning software, and value-based service contracts will lead account consolidation in USA.

USA Knee Replacement Market Trends

• Robotics, Navigation, And Data-Driven Balancing
  Surgeons in USA are leveraging robotic arms and imageless navigation to achieve reproducible alignment and soft-tissue balance, reducing outliers linked to dissatisfaction and early failure. Intraoperative analytics quantify gaps, loads, and range of motion, enabling data-guided releases rather than heuristic adjustments. Over time, aggregated case data inform planning templates for phenotypes (varus, valgus, stiff knees), raising consistency across teams and sites. Robotic ecosystems also streamline workflows with smaller trays and targeted resections that reduce OR time variability. As capital is justified through throughput, accuracy, and marketing pull, robotics becomes a strategic differentiator for hospital and ASC networks in USA.

• Shift To Outpatient And ERAS-Enabled Care Pathways
  ERAS protocols in USA—multimodal analgesia, regional blocks, and opioid-sparing strategies—are compressing length of stay and enabling same-day discharge for appropriate candidates. Standardized order sets, prehab education, and caregiver engagement lower complications and readmissions, easing payer concerns about ASC migration. Digital check-ins and remote vitals monitoring maintain safety while reducing in-person visits, which is attractive in capacity-constrained systems. Implant and instrument choices increasingly reflect ASC constraints: efficient trays, quick cementing, and minimal footprint robotics. As programs mature, site-of-care optimization becomes a primary lever for cost containment and patient experience in USA.

• Cementless Fixation And Advanced Bearing Materials
  Younger, active patients in USA are driving interest in cementless tibial/femoral fixation, aiming for long-term biological stability and simpler revisions. Modern porous coatings and surface chemistries promote osseointegration while preserving initial stability, reducing radiolucent lines seen with earlier designs. On the bearing side, highly crosslinked, vitamin-E stabilized polyethylene and alternative inserts improve wear resistance without sacrificing toughness. Together, these advances support longer service life, potentially delaying first revision in high-demand cohorts. As survivorship data accumulates, cementless options are moving from niche to routine in select indications across USA.

• Personalized Kinematics And Medial-Pivot/Anatomic Designs
  Dissatisfaction after perfectly aligned TKAs has pushed USA surgeons toward kinematics-aligned targets and designs that better mimic native rollback and medial stability. Medial-pivot and anatomic J-curves aim to restore natural feel, improving stair performance and patient-reported outcomes. Patient-specific planning and PS instrumentation reduce soft-tissue disruption and cut time, while preserving options for intraoperative adjustments. As PROMs and gait analytics become procurement criteria, designs with proven functional superiority gain formulary preference. Personalization thus migrates from marketing narrative to measurable outcome driver in USA.

• Digital Rehab, Remote Monitoring, And Outcome Registries
  Post-op engagement platforms in USA track ROM, pain, steps, and adherence, surfacing early risks for stiffness or infection and enabling tailored interventions. Gamified tele-rehab reduces therapy drop-off, while automated education improves home safety and wound care. Health systems integrate PROMs (OKS, KOOS) and wearable data into registries to benchmark surgeons and implants, informing contracting and quality bonuses. Over time, closed-loop data from plan to rehab guides continuous improvement and substantiates value-based claims. Digital follow-through becomes a core element of competitive differentiation for vendors and providers in USA.

Market Growth Drivers

• Aging Population, Obesity, And Osteoarthritis Prevalence
  In USA, demographic aging and rising BMI elevate osteoarthritis severity and symptom burden, expanding the pool eligible for surgery. Earlier presentation and improved referral pathways shift more patients to definitive treatment after conservative therapies plateau. As activity expectations remain high among seniors, surgical demand grows for durable solutions that restore mobility and independence. Public health messaging and improved access to orthopedic evaluation further convert latent need into procedures. These structural epidemiologic factors underpin steady primary TKA/UKA volume growth through 2031.

• Technology That Improves Accuracy, Throughput, and Satisfaction
  Robotics, navigation, and patient-specific planning reduce alignment and soft-tissue outliers, which correlate with revisions and dissatisfaction. Streamlined trays and efficient bone preparation compress operative time and sterilization burden, increasing daily case capacity. Better accuracy supports faster rehab and fewer PT visits, reinforcing payer acceptance of outpatient sites. When combined with modern bearings and cementless options, these technologies enhance survivorship and perceived value. The resulting clinical and operational gains justify premium ecosystems in USA.

• ASC Expansion And Bundled Payment Momentum
  Payers in USA incentivize migration to ASCs via site-differential reimbursement and bundled episodes that reward low complications and efficient post-acute care. Health systems respond with standardized pathways, preferred implant formularies, and home-focused rehab networks. Predictable, lower-cost settings broaden access and free inpatient capacity for complex cases. Vendors that tailor kits and support services for ASC workflows gain share as administrators prioritize reliability and simplicity. The financial and capacity benefits make ASC growth a durable driver of market expansion.

• Material Science And Fixation Advancements
  Improvements in polyethylene chemistry, tibial baseplate designs, and porous coatings translate into lower wear and stronger fixation. These advances expand indications for younger, more active patients who previously deferred surgery due to longevity concerns. Reduced wear also lessens osteolysis risk, lowering long-term revision rates and overall system cost. As survivorship curves improve, confidence rises among surgeons and patients, accelerating adoption. Material and fixation innovation remains a core catalyst for sustained market growth in USA.

• Data, Registries, And Value-Based Care Alignment
  National and regional registries in USA provide real-world evidence on implant survivorship, PROMs, and complication profiles, guiding purchasing and technique choices. Transparent outcomes enable risk-adjusted benchmarking, which aligns surgeon incentives with standardized best practices. Value-based contracts tie reimbursement to readmissions, infection rates, and functional gains, rewarding programs that deliver consistent results. Vendors supporting data capture and analytics strengthen partnerships with health systems. This evidence-driven environment favors platforms with proven performance and service support.

Challenges In The Market

• Cost Pressures, Reimbursement Variability, And Capital Constraints
  Hospitals and ASCs in USA face budget scrutiny; robotics and premium implants require clear ROI via throughput, outcomes, or marketing benefits. Regional reimbursement differences and prior-auth hurdles can delay surgery and complicate case scheduling. Bundled payments compress margins, pushing procurement toward standardized implants and fewer trays, which can constrain surgeon preference. Capital scarcity delays technology refresh cycles despite clinical interest. Navigating these financial realities is essential for sustained adoption.

• Workforce Shortages And Training Load
  Perioperative staffing gaps and turnover in USA strain OR scheduling and limit capacity to onboard new technology. Robotic and navigation systems demand dedicated training and proctoring that compete with clinical time. Inconsistent team composition increases setup variability and case times, blunting expected efficiency gains. Vendors must supply robust education, on-site support, and simplified workflows to maintain momentum. Without sustained training, technology underperforms and faces pushback.

• Revision Complexity And Supply Of Constraint/Revision Options
  As the primary installed base grows, revisions rise due to infection, instability, or aseptic loosening, requiring augments, cones, and stems that add cost and operative time. Inventory breadth for complex cases is challenging in ASCs and smaller hospitals in USA. Surgical exposure, bone loss management, and soft-tissue deficits raise complication risks and length of stay. Programs need clear pathways and regional centers of excellence to handle complexity. Insufficient revision capability can degrade overall outcomes and economics.

• Infection Prevention And Perioperative Optimization
  Periprosthetic joint infection, though infrequent, carries high clinical and financial consequences in USA. Optimizing glycemic control, nutrition, and decolonization requires cross-disciplinary coordination that is uneven across providers. Sterile processing variability and tray complexity can increase bioburden risk. Tight protocols and surveillance are necessary to protect gains from technology adoption. Persistent variation in optimization threatens readmission and revision metrics under value-based contracts.

• Equity, Access, And Patient Engagement
  Disparities in referral, insurance coverage, and rehab access create unequal outcomes in USA. Limited digital literacy or broadband can hinder remote rehab adherence, particularly in rural cohorts. Language and cultural barriers reduce prehab participation and post-op compliance. Programs must invest in multilingual education, transportation support, and hybrid rehab models to close gaps. Without inclusive design, satisfaction and PROMs lag despite technical success.

USA Knee Replacement Market Segmentation

By Procedure Type

• Total Knee Arthroplasty (TKA)

• Unicompartmental/Partial Knee Arthroplasty (UKA)

• Revision Knee Arthroplasty

By Fixation Method

• Cemented

• Cementless/Hybrid

By Bearing/Design

• Cruciate-Retaining (CR)

• Posterior-Stabilized (PS)

• Medial-Pivot/Anatomic Designs

• Mobile-Bearing

By Technology Adoption

• Conventional Instrumentation

• Computer-Assisted/Navigation

• Robotic-Assisted Surgery

• Patient-Specific Instrumentation

By End-User

• Hospitals

• Ambulatory Surgical Centers (ASCs)

• Orthopedic Specialty Centers

By Distribution/Contracting Model

• Capital Purchase (Implants/Robotics)

• Rental/Per-Procedure Robotics

• Bundled/Value-Based Agreements

Leading Key Players

• Zimmer Biomet

• Stryker

• DePuy Synthes (Johnson & Johnson)

• Smith+Nephew

• Medacta

• Corin Group

• MicroPort Orthopedics

• B. Braun Aesculap

• Exactech

• DJO/Enovis

Recent Developments

• Stryker expanded robotic-assisted knee indications in USA with workflow updates that reduce instrument trays and turnover time.

• Zimmer Biomet launched cementless TKA options in USA featuring porous surfaces and vitamin-E stabilized polyethylene bearings.

• DePuy Synthes introduced kinematics-aligned planning software in USA integrated with navigation for data-driven ligament balancing.

• Smith+Nephew rolled out ASC-focused instrument sets in USA with streamlined sterilization and rapid room turnover support.

• Medacta partnered with health systems in USA to deploy patient-specific instrumentation and digital rehab pathways for outpatient knees.

This Market Report Will Answer The Following Questions

1. What is the projected size and CAGR of the USA Knee Replacement Market by 2031?

2. How will robotics, navigation, and kinematics-aligned strategies improve outcomes and throughput in USA?

3. Which site-of-care models—hospital vs. ASC—optimize cost, safety, and patient satisfaction in USA?

4. What challenges—cost pressures, workforce, revisions, infection prevention—must stakeholders address to sustain value in USA?

5. Who are the leading players, and how do implant design, fixation, and digital ecosystems shape competitive positioning in USA?