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A membrane that can be induced to resonate and whose frequency can be monitored is described as a micro-electro-mechanical system (MEMS) device.
The membrane can be attached to chemical moieties, which can be chosen to have an affinity for molecules of interest, particularly biological molecules.
The membrane’s mass is increased and the resonance frequency is altered when the molecules of interest bind to the moieties.
It is possible to determine the approximate concentration of the molecules of interest and the presence of the molecules of interest by monitoring the resonance.
Additionally, a variety of moieties with affinity for a variety of molecules of interest can be deposited on the membrane in such a way that the sensor can identify which molecules of interest may or may not be present and which may or may not be present.
The Global Membrane based sensor market accounted for $XX Billion in 2021 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2022 to 2030.
A Novel Membrane-Based Sensor For Studying Electrochemical Reactions In Cultured Cells Or Tissues.
The membrane sensor prevents sensitivity loss by recording electrical signals from a cell culture without signal dilution.
In addition, the membrane’s porosity enables more effective nutrient uptake and molecule release thanks to its similarity to existing culturing methods.
Electron beam evaporation was used to fabricate the patterned sensor electrodes on a porous membrane.Cyclic voltammetry and chronoamperometry were used to evaluate the membrane electrodes’ electrochemical performance.
Synthetic dopamine was detected down to a concentration of 3.1 pM, and dopamine release from cultured PC12 cells was successfully measured in order to demonstrate the membrane-sensor’s functionality.
The PC12 cell culture experiments demonstrated that the membrane sensor was suitable for bio-applications as a cell culture substrate.
In cell cultures, real-time measurements of dopamine exocytosis were taken, and the transmitter release was recorded right at the point of release.
The new membrane-sensor adds new functionality to conventional culturing techniques, allowing for sensitive continuous in vitro monitoring in a manner that closely resembles in vivo conditions.
