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The Biofilm Monitoring System can identify the earliest stages of bacterial colonisation (down to 1% of the surface covered by microorganisms) and, using this information, can manually or automatically adjust and optimise cleaning treatments and biocide treatments (in industrial water systems, cooling towers, pure water lines, etc.), allowing for simultaneous evaluation of the cleaning’s efficacy.
Biofilm sensors have already been deployed, with very positive outcomes, in a number of industrial applications (cooling water systems, industrial water treatment, desalination, food processing, paper mills, etc).
The Global Biofilm sensor market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
Monitoring biofilms may reveal vital details about basic biofilm-related processes. With that knowledge, researchers can better understand how bacteria function and identify strategies for avoiding bacterial illnesses in the future.
Microscopical, spectrochemical, electrochemical, and piezoelectric techniques are among the methods used for biofilm analysis. Bacterial biofilms are communities of surface-associated microorganisms that live in cellular clusters or micro-colonies and are encapsulated in a complex matrix made of an extracellular polymeric substance.
These micro-colonies are separated from one another by open water channels, which serve as a circulatory system to improve nutrient diffusion and facilitate the removal of metabolic waste products. However, the development of novel strategies for the real-time monitoring of biochemical, in particular metabolic activity, of bacterial species during the formation, life, and eradication of biofilms is of great potential importance.
All these methods significantly advance our understanding of the bio-process related to biofilm formation and eradication.
The oxide layer of the SiNW was novel surface modified by an active redox system composed 9,10-dihydroxyanthracene/9,10-anthraquinone to produce a chemically-gated FET array, which allowed for the detection and monitoring of the metabolic activity of bacterial biofilms in high-ionic-strength solutions.
Metabolites can be transformed to H2O2 by oxidases and then seen by nanosensors through enzymatic processes.It has been proven that glucose metabolites can be successfully detected in high-ionic-strength solutions, such as bacterial medium, without pre-processing of tiny volume samples under various conditions and treatments.
The biofilms were subjected to antibiotic treatments with various modes of action and contrasted with untreated biofilms. SiNW-FET devices could be used to further examine biofilms as they are being treated with antibiotics in order to learn more about the bioprocess that takes place there. Additionally, the innovative nanosensor might be used as a monitoring tool to determine the best treatment for getting rid of the biofilm.
