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The TCSPC Lifetime Fluorometer is a scientific tool typically used in the fields of biochemistry and biophysics to determine the fluorescence lifespan of molecules. The temporal difference between the excitation and emission of a fluorescent molecule is precisely measured using time-correlated single-photon counting (TCSPC).
Fluorescence lifetime measurements offer crucial knowledge on the interactions and molecular surroundings of fluorescent substances such proteins, DNA, and lipids.
The efficiency of energy transfer between chromophores, conformational changes in proteins, binding interactions of ligands, and other significant characteristics of biomolecules can all be identified by measuring the lifespan of the fluorescence signal.
A unique kind of TCSPC equipment created especially for fluorescence lifetime measurements is the TCSPS Lifetime Fluorometer.
A pulsed laser, a sample holder, a detector, and a data collecting system are the standard components. The fluorescent molecules in the sample are excited by the laser, and a sensitive photodetector picks up the produced fluorescence.
TCSPC is used to quantify the lag between excitation and emission, and the fluorescence lifetime is computed from this measurement.
The TCSPS Lifetime Fluorometer is an effective tool for analysing the molecular characteristics of biological systems and has a wide range of applications in areas like drug development, protein structure characterization, and biomolecule dynamics.
Global tcspc lifetime fluorometer market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
The new Ultima TCSPC Fluorescence Lifetime system, designed for quick lifespan measurements, was just released by HORIBA Scientific.
The new Ultima fluorometer offers the greatest performance photon counting lifetime system currently on the market by combining the most recent high temporal resolution TCSPC electronics, interchangeable high speed light source, and detector technologies, with HORIBA Scientific’s FluoroCube.
The Ultima can measure the shortest lives of any comparable commercial device thanks to its 400 fs/point time resolution.
The Ultima is also the simplest to use due to its measurement range of 100 ns to seconds, adaptability of 16k time channels, and ease of a USB Computer connection.
To accommodate practically any experimental setup, the Ultima can also be customised for work with MCPs, fs lasers, NIR detectors, and excitation and emission monochromators.
