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using ion mobility spectrometry The mobility of the molecules in a carrier buffer gas is used as a criterion for separating and identifying ionised molecules that are present in the gas phase. Although it is frequently employed for military or security purposes, such as the detection of drugs and explosives, the technique also has a wide range of uses in laboratory analysis, including the study of small and large biomolecules.
Although IMS instruments are highly sensitive standalone devices, they are frequently combined with mass spectrometry, gas chromatography, or high-performance liquid chromatography to achieve a multidimensional separation.
The Global Ion Mobility Spectrometer Market accounted for $XX Billion in 2022 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2023 to 2030.
Mobie, a high-resolution ion mobility (HRIM) mass spectrometry device, has been released by Mobilion Systems for use in workflows for monitoring vital quality factors during the development of biopharmaceutical drugs.
According to the business, the new product is based on structures for lossless ion manipulation (SLIM) technology, which extends the ion mobility path beyond conventional devices and results in more thorough separations to expose molecules that were previously invisible.
According to the business, the separation technique addresses characterisation issues that scientists have throughout the development of biopharmaceutical drugs and quality control. Scientists can now distinguish and identify molecular structures that would either take too much time or be challenging to find using techniques like liquid chromatography thanks to the company’s SLIM technology.
In comparison to traditional separation techniques, Mobie can analyse a range of analyte classes, including peptides, proteins, lipids, and glycans, five to sixty times faster.
In order to connect its first HRIM system with Agilent’s 6500 series of quadrupole time-of-flight (Q-TOF) mass spectrometers, Mobilion and Agilent Technologies announced their agreement. More thorough separations are produced by the combination of technologies, revealing molecules that weren’t before visible.
According to the companies, the technologies work together to give pharmaceutical companies a tool for creating safer and more effective biologic therapies as well as a tool for helping university researchers find new biomarkers.
Protein Metrics’ Byos biopharma software suite and Mobilion’s SLIM solution were integrated earlier this year, according to a joint announcement by the two companies. The alliance, according to the business, offers a complete workflow solution with quick, simple data processing.
