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Identification and selection of cells, followed by the division of diverse cell kinds, constitute the process of cell sorting. It is used to create a homogenous cell population from mixed cell sample. Target cells can be marked with a fluorescent dye selectively using antibodies and the FACS method.
Cell sorting is the process of selecting and identifying cells, followed by the separation of the various cell species. Cells can be categorised based on markers as well as other factors such as shape.
Fluorescently labelled antibodies are used in many cell sorting techniques to identify the cells of interest and thus separate target cells from undesirable cells. These antibodies only bind to particular cell types or cells at particular stages of cellular development.
To create a homogeneous cell population from heterogeneous cell samples, cell sorting is frequently utilised. For most research projects, only a particular type of immune cell is relevant. Bone marrow extracts, for instance, contain a variety of immune cells in various stages of development and differentiation.
Through the use of CD19/CD20 markers, B-cells, for instance, can be recognised and subsequently distinguished from other immune cells in the bone marrow extract.
It has been demonstrated through oncology and cancer research that tumours not only include tumour cells but that immune cells are also invading the tumour tissue.
Additionally, due to acquired cancer mutations, the tumour cells differ from one another in terms of their genomic information, which adds to the tumor’s heterogeneity.
Global cell sorting platform market accounted for $XX Billion in 2023 and is anticipated to reach $XX Billion by 2030, registering a CAGR of XX% from 2024 to 2030.
The Bigfoot Spectral Cell Sorter has been introduced by Thermo Fisher Scientific in India. The groundbreaking cell sorting system combines spectral sorting and analysis with traditional sorting to produce quick, simple-to-use cell sorting.
Scientists can separate living, homogenous cell populations via cell sorting to address important issues such as stem cell development, cellular responses to medications, and cellular alterations that occur under specific conditions.
The Bigfoot Spectral Cell Sorter was created to solve problems faced by researchers and offers special advantages like:
Scale speed: The device speeds up sorting up to ten times faster than rivals.Bigfoot Spectrum Cell Sorter offers adaptability for both conventional fluorescence detection and spectral unmixing because it can be set up with up to nine lasers and 60 detectors.
